Fig 1.
Distribution of height-adjusted total liver volume (htTLV) according to age and gender.
(A) Box plot of median (and inter-quartile range) of htTLV by age decades. The median htTLV was higher in males of age <40 and females ≥70 years (*P < 0.05 for gender difference). The skewing of htTLV towards larger size is most noticeable in females across all strata above 40 years of age, (P value for Jonckheere–Terpstra test for trend <0.001). (B) A scatter plot of htTLV by age and gender. Moderate PLD is moderately enriched by females and severe PLD, extremely enriched by females.
Fig 2.
Prevalence of abdominal symptoms and hepatic complications.
(A) The prevalence of hepatic complications of all subjects. (B) The prevalence of abdominal symptoms on a three-point scale. Back pain and flank pain were most prevalent. Abdominal fullness and early satiety were common among moderate to severe symptoms (point 2 or 3).
Fig 3.
Likelihood (log odds) of having complications or two or more pressure-related symptoms according to htTLV and the correlation between htTLV and htTKV or htTLV + htTKV.
(A) Positive likelihood of having pressure-related complications at htTLV ≥2,100 mL/m. (B) Positive likelihood of having two or more pressure–related symptoms at htTLV ≥ 1,600 mL/m. Note that htTLV≥3,200 mL/m was indicated as the threshold for severe polycystic liver disease. (C) The proportion of subjects and ratio of male to female according to htTLV of 1,600 mL/m and htTKV of 1,000 mL/m. (D) Correlation between htTLV and htTLV + htTKV.
Table 1.
Prevalence of hepatic complications according to no or mild, moderate, and severe PLD.
Table 2.
Prevalence of abdominal symptoms according to PLD disease severity.
Table 3.
Multivariate binominal logistic regression analysis of hepatic complications.
Table 4.
Multivariate binominal logistic regression analysis of symptoms.