Fig 1.
Fundus images of Type 1 ROP and its laser treatment outcomes in large preterm infants.
1A-4A: Brush-like retinal neovascularization was observed on the posterior margin of avascular peripheral retina, located in zone II retina. All eyes had increased venous dilation and arteriolar tortuosity of the posterior retinal vessels (plus disease). 1B-3B: ROP regressed following laser treatment, with absence of peripheral retinal vascularization, retinal pigmentary changes and vitreoretinal interface changes. 4B: Temporal retinal detachment developed at 4 weeks after laser treatment, associated with macular heterotopia, straightening of blood vessels in temporal arcade and dragging of retina over optic disc.
Table 1.
The infants’ demographic and ROP information in the study.
Table 2.
Risk factors of Type 1 ROP in the infants of the study.
Table 3.
Sequelae of ROP regression following laser treatment in the study.
Fig 2.
Comparison of Type 1 ROP location between large and small preterm infants.
Type 1 ROP was in zone II retina of all eyes in the study, while 41% of them were in zone I retina of the small preterm infants. BW: birth weight. Data source of infants BW < 1251 g: the ET-ROP study [10].
Fig 3.
Comparison of Type 1 ROP stage between large and small preterm infants.
The percentage of stage 3 ROP was significantly lower in large preterm infants than that of small preterm infants (33% vs. 53%, p = 0.007). BW: birth weight. Data source of infants BW < 1251 g: the ET-ROP study [10].
Fig 4.
Comparison of Type 1 ROP evolution between large and small preterm infants following laser treatment.
ROP regressed in similar percentage of eyes in large and small preterm infants (96% vs. 91%, p = 0.25). BW: birth weight. Data source of infants BW < 1251 g: the ET-ROP study [10].