Fig 1.
Example photographs for oocyte scoring system.
The figure represents the oocyte grading system for the six morphological characteristics analyzed in this project (Morphology, Size, Cytoplasm, ZP, PVS and PB). For each oocyte, each single characteristic was graded as worst (-1), average (0), or best (1) creating a TOS by adding up individual parameter assessments.
Table 1.
Patient characteristics.
Fig 2.
Distribution of TOS among studied patients.
Fig 2 is the histogram of Total Score. The Total Score distribution is not symmetric.
Table 2.
Characteristics of 594 oocytes.
Table 3.
Univariate associations of oocyte characteristics with Day 3 embryo ≥ 8 cells.
Table 4.
Univariate associations of oocyte characteristics with Day 3 embryo Grade.
Fig 3.
ROC curves for oocyte and embryo scores.
Among the 69 patients with embryos of Grade 4 or better available for transfer 23 achieved Clinical Pregnancy. When the analysis was restricted to the 69 transfers with Good quality embryos (≥ Grade 4) the Oocyte Scoring System (TOS) (AUC±SE 0.863±0.044, oocyte score) provided significantly greater predictive value for clinical pregnancy compared to the embryo grade alone (AUC 0.646 ± 0.072, embryo grade) p = 0.015.