Table 1.
patients’ main characteristics.
Table 2.
Liver histology.
Table 3.
Cytokine levels (pg/mL) in the overall patient group.
Table 4.
Cytokine levels in different groups of patients.
Table 5.
Δ cytokine levels in different groups of patients.
Fig 1.
Th1/Th2, M1/M2 and IL10/IL17a ratios.
Th1/Th2, M1/M2 and IL10/IL17a ratios in patients respectively without and with portal hypertension (PH) (a: NO PH vs PH), in patients without an established diagnosis of Non-alcoholic Steatohepatitis (NASH), in comparison with NASH patients (b: NO NASH vs NASH) and in patients without and with diabetes mellitus (DM) (c: NO DM vs DM). IL: interleukin, INFγ: interferonγ, TNFα: tumour necrosis factor α, #: statistically significant difference between groups (p<0.05).
Fig 2.
Significant correlations between M1/M2 ratio and clinical features.
M1/M2 significant correlations with the respective correlation coefficient (p<0.05). The peripheral (P)-M1/M2 ratio positively correlated with steatosis grade and with fasting insulin. The hepatic venous (HV)-M1/M2 ratio positively correlated with fasting insulin.
Fig 3.
Significant correlations between IL6 levels and clinical features.
IL6 level in peripheral blood (P) correlated with the visceral fat amount.
Fig 4.
Significant correlations between IL10/IL17a ratio and clinical features.
IL10/IL17a Significant correlation with the respective correlation coefficient (p<0.05). The peripheral (P)- and hepatic venous (HV)-IL10/IL17 ratios negatively correlated with fasting insulin.