Fig 1.
Regions-of-Interest for extraction of diffusion parameters.
A preview of the Regions-of-Interest (in red) used in the analysis overlaid on the FMRIB58 fractional anisotropy standard space image. (A) White matter underlying the pre-central gyrus. (B) Corona Radiata. (C) Posterior Limb of Internal Capsule (D) Cerebral Peduncles (E) Genu of the Corpus Callosum.
Table 1.
Characteristics of the included patients.
Fig 2.
Infarct probability map of the patient cohort.
Infarct probability map overlaid on a diffusion-weighted volume of a selected patient. Color map corresponds to the percentage of patients with infarcted tissue in a given voxel. Z-coordinates are in MNI space.
Table 2.
Ratios of diffusion metrics in the four Regions-Of-Interest and control region.
Table 3.
Global and partial correlations between diffusion metrics of the corona radiata, infarct volume, and outcome.
Table 4.
Receiver-Operator Curve (ROC) models for CoRad-rAD.
Fig 3.
Positive and Negative Predictive Values for good outcome as a function of CoRad-rAD values.
The positive predictive values (PPV in green) correspond to the CoRad-rAD values above the threshold (x-axis). The negative predictive values (NPV in red) correspond to the CoRad-rAD values below the threshold. (A) Good outcome is assessed by NIHSS item 5 for upper limb (UL) scores 0–1 at day 7 post-stroke. (B) Very good outcome is assessed by mRS ≤ 1 at 3 months post-stroke. (C) Good outcome is assessed by mRS ≤ 2.