Fig 1.
Reconstruction of microdialysis probe placement in the medial and lateral dorsal striatum of rats used for analysis. Illustrations adapted from Paxinos and Watson.
Table 1.
Values of average baseline (B1-B4) samples for each group.
Values are group means (SEM) expressed in pg/ul.
Fig 2.
Serotonin concentrations in the dorsal striatum.
A) Mean extracellular 5-HT levels expressed as a percentage of baseline samples in the dorsal medial striatum (DMS) of control rats during each 20 min sampling period. B) same as A but for rats exposed to uncontrollable stress (Stress). C) Combined mean post-shock (FS-P4) extracellular 5-HT levels expressed as a percentage of baseline samples (grey dashed line) in the DMS for each group. D) Mean extracellular 5-HT levels expressed as a percentage of baseline samples in the dorsal lateral striatum (DLS) of control rats during each 20 min sampling period. E) same as D but for rats exposed to uncontrollable stress (Stress). F) Combined mean post-shock (FS-P4) extracellular 5-HT levels expressed as a percentage of baseline samples (grey dashed line) in the DLS for each group. aP<0.01 different from B1, B2, B3, or B4 in Sedentary Stress; bP<0.05 Sedentary Stress from Sedentary Control at FS and P1 sampling periods; cP<0.05 Sedentary Stress from Running Stress at FS sampling period; dP<0.05 P3 from B1 or B4 in Sedentary Stress group; e P<0.05 Sedentary Stress from Sedentary Control, Running Control, and Running Stress; fP<0.05 from Running Control and Running Stress; gP<0.05 from baseline (grey dashed line)
Fig 3.
Dopamine concentrations in the dorsal striatum.
A) Mean extracellular DA levels expressed as a percentage of baseline samples in the dorsal medial striatum (DMS) of control rats during each 20 min sampling period. B) same as A but for rats exposed to uncontrollable stress (Stress). C) Combined mean post-shock (FS-P4) extracellular DA levels expressed as a percentage of baseline samples (grey dashed line) in the DMS for each group. D) Mean extracellular DA levels expressed as a percentage of baseline samples in the dorsal lateral striatum (DLS) of control rats during each 20 min sampling period. E) same as D but for rats exposed to uncontrollable stress (Stress). F) Combined mean post-shock (FS-P4) extracellular DA levels expressed as a percentage of baseline samples (grey dashed line) in the DLS for each group. aP<0.05 at P1 from P4 within Running Control; bP<0.05 FS from B2 or B3 within Running Stress; cP<0.05 P1 from B3 within Running Stress; DP<0.05 P2 from B1, B2, or B3 within Running Stress; eP<0.05 at Running Stress from Sedentary Stress for respective sampling period; fP<0.01 from Sedentary Control, Sedentary Stress, Running Control; gP<0.001 main effect of exercise condition; hP<0.01 from baseline (grey dashed line)