Table 1.
Selected Primers for PCR and gene sequencing.
Table 2.
Clinic-pathologic and biologic data of the TNBC patients according to mutational status of PIK3CA.
Fig 1.
Morphologic and immunohistochemical features of Triple Negative Breast Cancer.
(A) Haematoxylin & Eosin stain illustrates a Triple Negative variant with features of high grade invasive ductal carcinoma (original magnification 100X); (B) Immunohistochemistry for EGFR displaying diffuse and moderate membranous and membranous-cytoplasmic immunoreactivity (original magnification 100X); (C) Immunohistochemistry for CK5/6 showing diffuse and intense cytoplasmic immunoreactivity (original magnification 100X); (D) Immunohistochemistry for p- AKT showing diffuse and intense nuclear immunoreactivity (original magnification 100X); (E) Immunohistochemistry for p-p44/42 MAPK displaying diffuse and intense nuclear-cytoplasmic immunoreactivity (original magnification 100X); (F) Immunostaining for PTEN showing diffuse and intense nuclear immunoreactivity (original magnification 100X).
Table 3.
Immunostaining data of the TNBC patients according to mutational status of PIK3CA.
Table 4.
Association between overall survival and clinic-pathological and molecular variables.