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Fig 1.

Enrollment, Participation, Follow-up, and Analysis of the patient group.

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Table 1.

Demographic characteristics of patients and controls subjects.

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Table 2.

Surgery and postoperative data in the patient group.

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Table 3.

Summary of neuropsychological assessment.

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Fig 2.

Association between attention (D-CAT1) and anesthesia (sevoflurane) in the patient group.

Residual plots with trend lines depicting the correlations between residuals in the multiple regression analyses, using the change ratio of D-CAT1 scores as the dependent variable, and the total dose of sevoflurane and other confounding factors as independent variables. Two patients who did not receive post-operative examination and 2 patients who were assigned as outliers of the sevoflurane dose were removed from the analysis. Therefore the data from 28 patients were analyzed. Abbreviations: D-CAT, digit cancellation task.

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Fig 3.

Regions showing the significant group (Pt/HC) by time (pre/post) interactions (right thalamus; p < 0.05, SVC).

The colored bar shows the scale of the t-value. Abbreviations: Rt, right; Pt, patients; HC, healthy controls; Pre, before surgery; Post, after surgery.

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