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Fig 1.

Trial flow chart.

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Fig 2.

Connection piece.

Cyto Set system enabling simultaneous use of 5 infusion bags.

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Table 1.

Treatment characteristics of 54 patients who underwent PPPD or palliative bypass procedure, and were randomized to the Standard or Restricted group. Data shown include fluid infusion data during the procedure, and i.v.* noradrenalin and diuresis at the end of operation.

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Table 2.

Results of scintigraphy performed preoperatively and 7 days postoperatively in 48 full protocol patients who underwent PPPD or palliative bypass procedure and were randomized to a Standard or a Restricted fluid protocol. The second part specifies 32 patients who only underwent a PPPD procedure and were randomized to a Standardized or a Restricted fluid protocol.

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Table 3.

Distribution of clinical delayed gastric emptying of 54 patients who underwent PPPD* or palliative bypass procedure with GJ and were randomized between a Standard or a Restricted intraoperative fluid protocol.

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Table 4.

Perioperative outcomes of 66 patients randomized between a Standard or Restricted intraoperative fluid protocol, who underwent PD* or palliative bypass procedure with GJ.

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Table 5.

Six year follow-up regarding survival in of 66 patients randomized between a Standard or Restricted intraoperative fluid protocol, who underwent PD* or palliative bypass procedure with GJ.

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Fig 3.

Kaplan Meier curve of cumulative survival.

6-year follow-up after operation, 66 patients randomized between a Standard or Restricted intraoperative fluid protocol. Data of 15 patients are not included (unknown status). Date of death unknown for 2 patients in standard group.

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