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Fig 1.

Diagrammatic Representation of Study Selection Flow conducted according to the PRISMA (Preferred reporting items for systematic reviews and meta-analyses) Statement.

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Table 1.

Study inclusion & exclusion criteria.

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Table 2.

Themes and subthemes emerged from the 57 articles included in the study.

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Table 3.

Legislations, Regulations and Policies for Orphan Drugs by Country.

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