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Table 1.

The databases (PubMed, Embase, Scopus, and Ichushi Web) that were queried and the search terms applied to identify potential publications for review.

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Fig 1.

Flow diagram for the selection of literature reviewed.

The abstract screening process resulted in 286 studies identified for detailed review of full-text articles. After this review, we further excluded studies that did not meet our definition of social media (e.g., Internet search, ProMED-mail) or discussed methods exclusively. We identified a total of 60 studies that met our eligibility criteria and addressed at least one of the two research questions. This process took over a year to complete because the authors donated their free time to review and analyze the literature.

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Fig 2.

Number of Studies Addressing Questions 1 and 2, Reviewed in Detail by Year Published (January 2000 –February 2013).

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Table 2.

Counts of Funding Agency Types and Their Direct Involvement in the Review Studies.

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Table 3.

Characteristics of 15 influenza-like illness studies addressing research question 1a.

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Table 4.

Characteristics of 6 infectious disease studies addressing research question 1a.

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Table 5.

Characteristics of 4 non-infectious disease studies addressing research question 1a.

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Table 6.

Characteristics of 4 medicine or vaccine studies addressing research question 1a.

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Table 7.

Characteristics of 5 “other” topic studies addressing research question 1a.

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Table 8.

Characteristics of 10 health risk behavior studies addressing research question 2a.

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Table 9.

Characteristics of 3 infectious diseases studies addressing research question 2a.

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Table 10.

Characteristics of 9 non-infectious diseases studies addressing research question 2a.

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Table 11.

Characteristics of 10 “other” topic studies addressing research question 2a.

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