Fig 1.
The distributions of the subtypes of genetic prion diseases.
A. Surveillance year distribution. The rates of genetic prion diseases among all diagnosed human prion diseases are shown by a blue triangle and a dotted line. B. Geographic distribution. The residences of the patients are given by province.
Fig 2.
The age of onset of patients of various genetic prion diseases.
A. Distribution of the age of onset based upon the types of disease. The median onset age of all 69 patients is indicated by a dotted line. The median onset age of each disease is illustrated with a short, red bar. B. Distribution of the age of onset based upon decade of life. C. Distribution of the age of onset based upon the disease type and decade of life.
Table 1.
The clinical manifestations of various human genetic prion diseases.
Table 2.
Family histories and PRNP sequencing results of various human genetic prion diseases.
Table 3.
CSF 14-3-3, MRI and EEG status in various human genetic prion diseases.
Table 4.
The time interval between disease onset and the initial neurologist visit, diagnosis and death of various human genetic prion disease patients.