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Table 1.

HBoV1-3 IgG stability among 109 constitutionally healthy children.

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Table 2.

Co-occurrence of IgM or viremia with human bocavirus 1, 2 or 3 primary IgG seroconversions among 109 constitutionally healthy children.

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Table 2 Expand

Table 3.

Infection-related symptoms during human bocavirus 1 and 2 primary seroconversions compared with those of the previous and subsequent sampling intervals.

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Table 3 Expand

Fig 1.

Human bocavirus 1–3 seroprevalences (dashed lines) and cumulative seroconversion rates (solid lines) in different age groups.

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Fig 2.

Pre-existing HBoV1 IgG reduces immune response against HBoV2 infection.

Two representative cases of PCR-verified HBoV2 infections without (child #52) or with (child #108) pre-existing HBoV1 IgG are shown. The red, blue and black data points respectively indicate whether the serum tested positive by PCR, tested negative by PCR, or was not tested by PCR. Although not shown in the graphs, both children tested negative for HBoV3- and 4-specific IgG.

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Fig 3.

Pre-existing HBoV2 IgG reduces immune response against HBoV1 infection.

Two illustrative cases of PCR-verified HBoV1 infections without (child #53) or with (child #122) pre-existing HBoV2 IgG are shown. The red, blue and black data points respectively indicate whether the serum tested positive by PCR, tested negative by PCR, or was not tested by PCR. The red open circle indicates a sample that was positive for HBoV1 IgM. Although not shown in the graphs, both children tested negative for HBoV3- and 4-specific IgG.

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Fig 3 Expand