Table 1.
Patient demographics and tumor characteristics.
Table 2.
Association of apparent diffusion coefficient (ADC) values (× 10−3 mm2s-1) measured by Observer 1 with pathologic and prognostic factors in breast lesions, using the whole lesion and small regions of interest (ROIs).
Fig 1.
Lesion differentiation in (A) dynamic contrast-enhanced magnetic resonance imaging (MRI, left) and in (B) diffusion-weighted imaging (DWI, right) of the right breast of a 41-year-old woman.
Fig 2.
Whole lesion (red) and small (yellow) region of interest (ROI) placement on a diffusion-weighted image (DWI) of the right breast of a 41-year-old woman.
Table 3.
Mean apparent diffusion coefficient (ADC) values (× 10−3 mm2s-1) of 3.0-Tesla using MRI from normal parenchyma, benign lesions, and malignant lesions, and ADC values’ utility in tumor characterization.
A review of the literature.
Fig 3.
Distribution of apparent diffusion coefficient (ADC) values in benign and malignant lesions in a) whole lesion and b) small regions of interest (ROIs).
ADC values (× 10−3 mm2s-1) of individual lesions are presented on the Y-axis. Black dots represent malignant lesions, and empty circles represent benign lesions. The line indicates the used cut-off values, 0.87 × 10−3 mm2s-1 for whole lesion ROIs and 0.69 × 10−3 mm2s-1 for small ROIs.
Fig 4.
Receiver operator characteristic curves of whole lesion (red line) and small (black line) regions of interest (ROIs).
Area under the curve values are 0.957 (whole lesion ROI) and 0.962 (small ROI).
Table 4.
Previous publications that address the correlation between apparent diffusion coefficient (ADC) values and prognostic factors in breast cancer.