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Table 1.

Clinical characteristics of patients (n = 30).

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Fig 1.

β-Catenin and Ki67 immunostaining in adjacent breast tissue to tumor or breast tumor tissue.

Adjacent breast tissue to tumor or breast tumor tissue labeled by indirect immunofluorescence for A/ β-catenin and B/ Ki67 (green) with DAPI as nuclear counterstain (blue).

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Fig 1 Expand

Table 2.

Comparison of proliferation markers (Ki67 and β-Catenin) in breast tissues adjacent to the tumor and tumor tissues of breast cancer patients based on immunohistochemistry staining.

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Table 2 Expand

Fig 2.

Adiponectin and Adiponectin receptors immunostaining in adjacent breast tissue to tumor or breast tumor tissue.

Adjacent breast tissue to tumor or breast tumor tissue labeled by indirect immunofluorescence for A/ Adiponectin, and B/ Adiponectin receptor 1 and C/ Adiponectin receptor 2 (red) with DAPI as nuclear counterstain (blue).

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Fig 3.

Leptin and Leptin receptor immunostaining in adjacent breast tissue to tumor or breast tumor tissue.

Adjacent breast tissue to tumor or breast tumor tissue labeled by indirect immunofluorescence for A/ Leptin and B/ Leptin receptor Ob-R (red) with DAPI as nuclear counterstain (blue).

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Fig 3 Expand

Table 3.

Comparison of adipokines and their receptors (AdipoR1, AdipoR2 and Ob-R), COXs, F2-isoprostanes, prostaglandin F, α-SMA and aromatase in breast tissues adjacent to the tumor and tumor tissues of breast cancer patients based on a score calculated from the staining intensity and percent of area immunostained tissues.

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Table 3 Expand

Fig 4.

COX-1 and COX-2 immunostaining in adjacent breast tissue to tumor or breast tumor tissue.

Adjacent breast tissue to tumor or breast tumor tissue labeled by indirect immunofluorescence for A/ COX-1 (red) and B/ COX-2 (green) with DAPI as nuclear counterstain (blue).

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Fig 4 Expand

Table 4.

Comparison of adipokines and their receptors (AdipoR1, AdipoR2 and Ob-R), COXs, aromatase, F2-isoprostanes, prostaglandin F, α-SMA and aromatase in breast tissues adjacent to the tumor and tumor tissues of breast cancer patients on the basis of percent of staining area.

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Table 4 Expand

Table 5.

Comparison of adipokines and their receptors (AdipoR1, AdipoR2 and Ob-R), COXs, F2-isoprostanes and prostaglandin F, α-SMA and aromatase in the breast tissues adjacent to the tumor and tumor tissues of breast cancer patients on the basis of staining intensity.

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Table 5 Expand

Fig 5.

F2-isoprostane and PGF immunostaning in adjacent breast tissue to tumor or breast tumor tissue.

Adjacent breast tissue to tumor or breast tumor tissue labeled by indirect immunofluorescence for A/ F2-isoprostane and B/ PGF (green) with DAPI as nuclear counterstain (blue).

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Fig 5 Expand

Fig 6.

Aromatase and α-SMA immunostaning in adjacent breast tissue to tumor or breast tumor tissue.

Adjacent breast tissue to tumor or breast tumor tissue labeled by indirect immunofluorescence for A/ Aromatase (red) and B/ α-SMA (green) with DAPI as nuclear counterstain (blue).

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Fig 6 Expand

Table 6.

Correlation between staining score values of COX-1 and adipokines and their receptors, aromatase and PGF in adjacent breast tissue and tumor tissues as performed by Pearson test.

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Table 6 Expand

Table 7.

Correlation between staining score values of COX-2 and adipokines and their receptors, aromatase, COX-1 and PGF in healthy and tumor tissues as performed by Pearson test.

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Table 7 Expand