Table 1.
Consensus criteria for the diagnosis of neurofibromatosis type 1*.
Fig 1.
PET/CT-guided percutaneous biopsy of a metabolically active pelvic soft-tissue tumor in 34-year-old man with NF1.
(a) Initial PET/CT discriminate FDG-avid portion at the right sciatic notch. (b) The needle is shown to be in most metabolically active portion of FDG-avid mass. Pathology results concluded to intermediate-grade MPNST. The tumor was unresectable and the patient was treated by chemotherapy (adriamycin and ifosfamide). He died 17 months after the diagnosis.
Table 2.
Baseline characteristics of patients.
Fig 2.
Histopathological results of the biopsy of the false negative case.
A. Atypical scattered cells with enlarged and hyperchromatic nuclei, in the absence of mitotic figures. B. Low Ki67 index (≈ 2%). C. Immunohistochemical staining for S100 is strongly positive.
Fig 3.
Histopathological results of the resected tumor of the false negative case.
A. The neoplastic cells in this area are cohesive. The cells have eosinophilic cytoplasm and nuclei with prominent nucleoli. Several mitoses are present. B. High Ki67 index (≈ 50%). C. Immunohistochemical staining for S100 is focal.