Table 1.
Simulation results of the Weibull rescue strategy using Weibull failure times and uniform censoring times.
Fig 1.
Results of the simulation study using Weibull failure times and uniform censoring times on Simon’s optimal design.
Table 2.
Bias obtained by each strategies according to the simulated data distributions on optimal Simon’s design with π = 40%.
Table 3.
Type I error rate and power provided by each strategy according to the simulated data distributions on optimal Simon’s design.
Fig 2.
Results of the simulation study using Log-logistic failure times and exponential censoring times on Simon’s optimal design.
Table 4.
Simulation results of type I and type II error rates obtained with the Weibull rescue strategy using Weibull failure times and uniform censoring times according to the visits calendar.
Table 5.
Simulation results obtained with the Weibull rescue strategy using Weibull failure times and uniform censoring times according to the error rate function.
Table 6.
Decisions that could be taken on real clinical trial data regarding the four strategies.