Fig 1.
Flow diagram for subject selection.
Baseline variables contain laboratory results (serum uric acid, serum creatinine, dipstick measured urine proteins, hemoglobin, high-density lipoprotein, triglycerides) physical examination (body mass index, systolic blood pressure, and diastolic blood pressure), and diabetes.
Table 1.
Baseline characteristics of subjects according to baseline uric acid levels and gender.
Table 2.
Adjusted hazard ratios for risk of renal dysfunction according to quartiles of baseline serum uric acid.
Fig 2.
Relationships of uric acid and kidney dysfunction and baseline kidney function.
Adjusted for baseline age, eGFR, systolic blood pressure, body mass index, hemoglobin, HDL cholesterol, triglyceride, urinary protein, and diabetes.
Fig 3.
Association between uric acid and eGFR slope according to baseline kidney function.
Multivariate-adjusted mean values of eGFR slope adjusted for baseline age, eGFR, systolic blood pressure, body mass index, hemoglobin, HDL cholesterol, triglyceride, urinary protein, and diabetes. Values are shown as mean ± SE. * P < 0.05, ** P < 0.01 compared with baseline serum uric acid 4.0–4.9 mg/dL.