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Table 1.

Parameters referring to each study as a whole.

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Table 2.

Parameters referring to each treatment group.

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Table 2 Expand

Fig 1.

Uniform Outcome adopted from RECIST.

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Table 3.

Quality Parameters.

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Table 3 Expand

Fig 2.

Flow chart of study selection.

It is distinguished between full-text articles and individual experimental outcomes within these articles. A full-text article can include several individual experiments, each of which describing one or several anti-angiogenic drug (candidates) outcomes.

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Fig 3.

A. Randomization over time. B. Conflict of Interest Statement over time.

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Table 4.

Contingency table of absolute outcome distribution within interventions in main focus of a study or comparison interventions.

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Table 4 Expand

Table 5.

Contingency table of relative outcome distribution within interventions in main focus of a study or comparison interventions.

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Table 5 Expand

Table 6.

Contingency table of relative outcome distribution with Sutent in main focus of a study or comparison interventions.

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Fig 4.

Frequency of experimental outcome 4 (progression) for studies with the same quality score.

n = 891.

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Fig 5.

SPSS output predictor importance.

Cutoff level = 0.4.

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Table 7.

Variable distribution within the four identified clusters.

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Table 7 Expand