Table 1.
Demographic Data of Patients (n = 135).
Table 2.
Factors Associated with the Change of Body Temperature (n = 135).
Fig 1.
The mean values of blood pressure (A), heart rate (B), and central body temperature (C) of the rats.
The central temperature in the Fr+Acetaminophen group was higher than the Fr+Arcoxia group. Two-way ANOVA with Duncan’s post hoc multiple comparisons was used. *p<0.05 for the Fr group compared with the Fr+Arcoxia group. #p<0.05 for the Fr group compared with the Fr+Acetaminophen group. §p<0.05 for the Fr+Arcoxia group compared with the Fr+Acetaminophen group.
Fig 2.
Influence on liver function by injury and different medications.
The serum levels of sGOT (A) and sGPT (B) in the Fr+Arcoxia group were lower than those in the Fr+Acetaminophen group after fracture. Two-way ANOVA with Duncan’s post hoc multiple comparisons was used. *p<0.05 for the Fr group compared with the Fr+Arcoxia group. #p<0.05 for the Fr group compared with the Fr+Acetaminophen group. §p<0.05 for the Fr+Arcoxia group compared with the Fr+Acetaminophen group.
Fig 3.
Influence on inflammation related cytokines TNF-alpha (A), IL-6 (B), and IL-10 (C) by injury and different medications.
Inflammation-related cytokine levels were significantly lower in the Fr+Arcoxia group. Two-way ANOVA with Spearman’s rho correlation was used.*p<0.05 for the Fr group compared with the Fr+Arcoxia group. #p<0.05 for the Fr group compared with the Fr+Acetaminophen group. §p<0.05 for the Fr+Arcoxia group compared with the Fr+Acetaminophen group.
Fig 4.
Influence on soft-tissue injury related enzymes by limb fracture and different medications.
In the Fr+Arcoxia group, the serum levels of CPK (A) and LDH (B) were significantly lower than those in Fr group and Fr+Acetaminophen group. Two-way ANOVA with Duncan’s post hoc multiple comparisons was used. *p<0.05 for the Fr group compared with the Fr+Arcoxia group. #p<0.05 for the Fr group compared with the Fr+Acetaminophen group. §p<0.05 for the Fr+Arcoxia group compared with the Fr+Acetaminophen group.