Fig 1.
Flow diagram of the literature search process for identifying studies.
Table 1.
Characteristics of included studies.
Fig 2.
(a) Meta-analysis of the overall response (ORR) of children vs. adults after mesenchymal stem cell (MSC) infusion. (b) Meta-analysis of the complete response (CR) of children vs. adults after MSC infusion. (c) Meta-analysis of the ORR with one or two involved organs vs. three involved organs after MSC infusion. (d) Meta-analysis of the CR with one or two involved organs vs. three involved organs after MSC infusion.
Fig 3.
(a) Meta-analysis of the overall response (ORR) with one involved organ vs. two involved organs after MSC infusion. (b) Meta-analysis of the complete response (CR) with one organ vs. two involved organs after MSC infusion. (c) Meta-analysis of the ORR of skin vs. gastrointestinal (GI) involvement after mesenchymal stem cell (MSC) infusion. (d) Meta-analysis of the CR of skin vs. GI involvement after MSC infusion.
Fig 4.
(a) Meta-analysis of the overall response (ORR) of skin vs. liver involvement after MSC infusion. (b) Meta-analysis of the complete response (CR) of skin vs. liver involvement after MSC infusion. (c) Meta-analysis of the ORR of gastrointestinal (GI) vs. liver involvement after mesenchymal stem cell (MSC) infusion. (d) Meta-analysis of the CR of GI vs. liver involvement after MSC infusion.
Fig 5.
(a) Meta-analysis of the overall response (ORR) of grade II vs. grade III–IV aGVHD after MSC infusion. (b) Meta-analysis of the complete response (CR) of grade II vs. grade III–IV aGVHD after MSC infusion. (c) Meta-analysis of the overall response after one infusion vs. more than one infusion. (d) Meta-analysis of the complete response after one infusion vs. more than one infusion.
Fig 6.
(a) Meta-analysis of the overall response (ORR) in induction therapy vs. completion therapy after MSC infusion. (b) Meta-analysis of the complete response (CR) in induction therapy vs. completion therapy after MSC infusion.