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Fig 1.

Map showing sampling sites.

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Fig 2.

Schematics of small-scale (A) and large-scale (B) TFF systems for the concentration and separation of microbes from water samples.

Abbreviations are as follows: Ret, retentate; Perm, permeate; kDa, kiloDalton; BC, bacterial concentration; BF, bacterial filtration; VC, viral concentration; VF, viral filtration; 30 kDa filter1, 30 kDa cut-off filter with regenerated cellulose material produced by Millipore; 30 kDa filter2, 30 kDa cut-off filter with polyethersulfone material produced by Millipore; 30 kDa filter3; 30 kDa cut-off filter with polyethersulfone material produced by Pall.

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Fig 3.

Efficiencies of 0.22 μm and 1000 kDa membranes filtration of bacteria (A) and viruses (B) with small-scale TFF system for contrasting marine environments.

Error bars depict the standard error of the mean expressed in percentage. *, p < 0.05; **, p < 0.01.

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Fig 4.

Efficiencies of filtration by bacteria-size membranes for bacteria (A) and viruses (B), and bacterial concentration by Millipore 0.22 μm membrane for samples from contrasting marine environments (C) in large-scale TFF system.

Error bars depict the standard error of the mean expressed in percentage. *, p < 0.05; **, p < 0.01.

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Fig 4 Expand

Fig 5.

The relationships between bacterial abundance and the efficiency of bacterial recovery

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Fig 6.

Efficiencies of viral filtration by three 30 kDa membranes for samples from contrasting marine environments in small-scale TFF(A). Comparison of viral filtration by Millipore and Pall 30 kDa cut-off membranes (B) and for samples from contrasting marine environments using Millipore 30 kDa cut-off membrane (C) in large-scale TFF.

Error bars depict the standard error of the mean expressed in percentage. *, p <0.05; **, p<0.01.

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Fig 6 Expand

Fig 7.

Comparison of samples from Station N2 in Xiamen coastal water (A) and Station WP5 in the western Pacific Ocean (B) in virus-like particle's Side Scatter (C) by flow cytometry.

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Fig 7 Expand