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Fig 1.

Overview of approach to developing the CAD algorithm in the RA cohort.

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Fig 2.

Validation of the CAD algorithm in the IBD cohort.

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Table 1.

Clinical characteristics of subjects in the RA, IBD and DM cohorts.

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Table 2.

Variables in the final CAD algorithm.

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Table 3.

Validation of accuracy of the two step classification of CAD (screening + algorithm) using structured data only, compared with the structured data + NLP.

Natural language processing = NLP; negative predictive value = NPV; positive predictive value = PPV.

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Table 3 Expand

Table 4.

Clinical characteristics of subjects classified with CAD in the RA, IBD and DM cohorts (PPV of CAD classification > = 90% PPV*).

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Table 5.

Unadjusted and adjusted odds ratios comparing risk of CAD in IBD and RA to DM.

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