Table 1.
Survey respondent demographics.
Table 2.
Mean genetic ancestry proportions determined via ancestry informative markers and HLA haplotype origin frequencies for subpopulations defined by reported race/ethnicity or geographic ancestry.
Table 3.
Correlation between self-identification measures and HLA origins and genetic ancestry.
Fig 1.
African and Amerindian genetic ancestry proportions (a,c) and HLA origin frequencies (b,d) are correlated with the number of grandparents with reported African and Latin American ancestry, respectively.
Genetic ancestry proportions were estimated from AIMs data using Structure and the HGDP reference set. For this analysis, k = 4, reflecting broad continental ancestry. For each subpopulation defined by the number of respondents’ grandparents with Sub-Saharan African/African American or Latin American ancestry, the percentage of individuals with zero, one or two African or Amerindian HLA haplotypes, respectively, was calculated. Individuals reporting one, two, three or four African-ancestry grandparents: n = 4; 4; 2; 21, respectively. Individuals reporting one, two, three or four Latin American-ancestry grandparents: n = 16; 21; 7; 38, respectively.