Fig 1.
Flowchart of HIV-infected patients who entered the study, and the proportion who developed tuberculosis, stratified by results of interferon-gamma release assay (IGRA).
Table 1.
Baseline Characteristics of Participants (N = 772).
Table 2.
Factors Associated with a Positive Interferon-Gamma Release Assay (IGRA) Result in 741 Participants*.
Fig 2.
Cumulative incidence of active tuberculosis disease over 5 years in a cohort of HIV-infected adults (N = 772).
Table 3.
Incident Rate and Risk Factors for Development of Incident Active Tuberculosis Disease in HIV-Infected Persons Using A Composite Risk Factor of High HIV Viral Load, Low CD4 Cell Count and IGRA Positivity (n = 772).
Fig 3.
Kaplan-Meier curve of HIV-infected patients who developed active tuberculosis disease by interferon-gamma release assay (IGRA) status, excluding 31 subjects with indeterminate results (N = 741).
Fig 4.
Kaplan-Meier curve to development of active tuberculosis disease by composite risk factor combining high HIV viral load of greater than 100,000 copies per mL, CD4 cell count and interferon-gamma release assay (IGRA)(N = 772).
Fig 5.
A multivariable algorithm to predict risk of active tuberculosis in people with HIV infection using a composite risk factor of HIV viral load, CD4 cell count and interferon-gamma release assay (IGRA) result.
Table 4.
Comparison of Different Approaches to Prevent Tuberculosis in People Living With HIV.