Table 1.
Baseline characteristics of men and women receiving chronic opioid therapy.
Table 2.
Escalation to high dose opioid therapy among men and womena.
Table 3.
Opioid-related death during chronic opioid therapy in men and women.
Fig 1.
Escalation to high dose opioid therapy among men and women.
Kaplan-Meier curves of opioid dose escalation to an average daily dose exceeding 200 mg of morphine (or equivalent) among men and women with at least 91 days of continuous opioid therapy. P values were determined by Cox proportional hazards regression.
Fig 2.
Opioid-related death among men and women.
Kaplan-Meier curves of opioid-related mortality among men and women with at least 91 days of continuous opioid therapy. P values were determined by Cox proportional hazards regression.