Table 1.
Demographic characteristics of the study participants.
Fig 1.
Average composition of the microbiota in fecal samples from normal and obese adolescents according to taxonomic rank.
The innermost ring of the donut plots for both normal and obese individuals shows the composition at the phylum level, whereas the middle and outermost rings show the composition at the family and genus levels, respectively. There was a marked difference in the average proportions of Bacteroides and Prevotella between normal and obese samples at the genus level. This trend persisted at the family level. However, there were no significant differences in the Bacteroidetes, Firmicutes, and Proteobacteria populations in samples from normal and obese adolescents at the phylum level. All microbiota representing > 1% (mean value) composition are shown.
Fig 2.
Mann-Whitney U test result showing differentially abundant microbiota in obese and normal adolescents.
A. Genus level and B. Family level.
Fig 3.
Mann-Whitney U test results at the phylum level.
A. Box plots showing similar abundance of the Bacteroidetes, Firmicutes, and Proteobacteria populations in normal and obese adolescents. B. The Firmicutes-to-Bacteroidetes ratio in the gut of normal and obese adolescents. There was no significant difference in F/B ratio between normal and obese adolescents.
Table 2.
List of taxa showing different abundance between obese and normal samples at the genus level.
Table 3.
List of taxa showing different abundance between obese and normal samples at the family level.
Table 4.
Association between the composition of the gut microbiota and body mass index (BMI) z-score and biochemical markers according to Pearson's r (p-value).
Table 5.
Association rules generated by association rule mining.