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Table 1.

Clinical and demographic characteristics of the study population stratified by age.

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Table 2.

Histopathological characteristics of radical prostatectomy specimens stratified by age.

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Fig 1.

ROC curve for the age group ≤ 49 years stratified for fPSA values ≤18% vs. >18% and ≤21% vs. >21%, respectively.

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Fig 2.

ROC curve for the age group ≤50–59 years stratified for fPSA values ≤18% vs. >18% and ≤21% vs. >21%, respectively.

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Fig 3.

ROC curve for the age group 60–69 years stratified for fPSA values ≤18% vs. >18% and ≤21% vs. >21%, respectively.

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Fig 4.

ROC curve for the age group ≥ 70 years stratified for fPSA values ≤18% vs. >18% and ≤21% vs. >21%, respectively.

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Table 3.

Proposed “new” PSA cut offs stratified by age.

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Table 4.

Comparison of “new” and “old” PSA cut offs concerning specificity (spec), sensitivity (sens) as well as positive (pos pred) and negative predictive (neg pred) values stratified by age.

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Table 5.

Recognized tumors (%) biopsied according to “old” PSA cut offs stratified by age.

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Table 6.

Recognized tumors (%) biopsied according to “new” PSA cut offs stratified by age.

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Table 7.

Reduction of number of biopsies with the “new” PSA cut offs stratified by age.

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