Fig 1.
Flow chart of patients’ inclusion and subgrouping.
Fig 2.
Seventy-year-old woman who underwent right hemicolectomy and right hemihepatectomy because transverse colon cancer with liver metastasis.
(A, B) On follow-up CT, two newly developed metastases are seen in the remaining left lobe of the liver (arrows). (c, d) On non-enhanced CT images, low attenuating lesions were suspected at the same locations as those on contrast-enhanced CT, but neither of the reviewers could detect these lesions.
Table 1.
Per patient analysis of diagnostic performance in detection of newly developed hepatic metastasis (Group A).
Table 2.
Per lesion analysis of diagnostic performance in detection of newly developed hepatic metastasis (Group A).
Table 3.
Comparison of size of the metastatic nodules in NECT and the reference standard.
Fig 3.
Seventy-two-year-old man who had known liver metastasis from gastric cancer.
a. On the portal venous phase, hepatic metastasis is seen in segment 4 of the liver. b. The size of the lesion appears similar in the non-enhanced CT image. This lesion was measured as 30 mm both in the contrast-enhanced CT (a) and non-enhanced CT (b) images. (c, d) On follow-up CT after 3 months, the lesion had increased in size. It was measured as 47 mm (57% interval increase) on contrast-enhanced CT, which suggested progression of disease (c). However, on non-enhanced CT, the mass was measured as 32 mm (7% interval increase), which suggested stable disease.
Table 4.
Accuracy of response evaluation based on the RECIST 1.1 criteria.