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Fig 1.

Flow diagram of studies considered for inclusion.

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Table 1.

Detailed characteristics of the studies.

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Table 2.

Summary of the studies analyzed.

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Fig 2.

Forest plot of the values of phosphorus.

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Fig 3.

Forest plot of the values of hepercalcemia (above 10.2 mg-dL).

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Fig 4.

Forest plot of the values of hepercalcemia (above 11.0 mg-dL).

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Fig 5.

Forest plot of sevelamer vs. calcium phosphate binders on CACS change.

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Fig 6.

Forest plot of sevelamer vs. calcium phosphate binders on ACS change.

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Table 3.

Details of the use of statins.

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Table 4.

Overall outcome summaries.

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Fig 7.

Funnel plot of the value of change of CACS.

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