Fig 1.
Figure describing different regions of mexAB-OprM operon which are amplified using different primers as shown.
Table 1.
Details of primers used for cloning of efflux pump genes.
Table 2.
MIC reduction assay using meropenem.
Table 3.
Antibiogram of P. aeruginosa with increased efflux pump activity.
Table 4.
MIC50 and MIC90 of efflux mediated carbapenem resistant P. aeruginosa isolates.
Fig 2.
Expression of mexA gene before and after single dose exposure with meropenem in bacteria.
Fig 3.
Expression of mexA gene before and after single dose exposure in transformants.
Fig 4.
REP PCR showing different REP types of P. aeruginosa possessing increased efflux pump activity.
Lane 1: Hyper ladder (1 kb); lane 2 to 20: test samples. 13 REP types can be seen in Lane 2, 3, 4, 5, 6, 8, 9, 12, 13, 14, 16, 17 and 18.