Fig 1.
Depiction of the measurements of PHE and hematoma.
(V1) Hyperdense hematoma regions and (V2) hypodense area surrounding hematoma for PHE. Volumes from all slices were summed: rPHE = V2/V1. PHE, perihematomal edema.
Table 1.
The clinical features of ICH patients and normal controls.
Fig 2.
Four serum miRNA levels were selected for verification using real-time qRT-PCR in individual ICH patients (n = 27) and healthy controls (n = 11).
Serum levels of miR-126, miR-146a, miR-let-7a, and miR-26a were significantly lower in ICH patients compared with those in the control group (**, P<0.01). miRNA expression levels are normalized to miR-191-5p (relative level). ICH, intracerebral hemorrhage.
Table 2.
Functional classification of changed miRNAs in ICH and their target genes.
Fig 3.
Spearman correlation analysis of serum miR-126, miR-146a, miR-let-7a, and miR-26a levels with rPHE in samples from ICH patients (n = 27).
Note that serum levels of (A) miR-126, but not (B–D) miR-146a, miR-let-7a, or miR-26a, were significantly correlated with rPHE. rPHE, relative perihematomal edema.
Table 3.
Spearman correlation analysis between the level of serum miR-126 and the clinical characteristics of the ICH patients.