Fig 1.
Cohort definition and observation period of the study.
Fig 2.
Flow chart of inclusion and exclusion criteria and remaining medication profiles/patients.
Table 1.
Cohort characteristics of the main study cohort at the index date.
Fig 3.
Distribution of Medication Possession Ratio.
Fig 4.
Median Medication Possession Ratios of the four DMD groups.
Fig 5.
Main analysis: Overview of compliance and persistence in the DMD groups over an observation period of 24 months.
Fig 6.
Main analysis: Kaplan-Meier persistence curves of the 4 DMD groups within the observation period of 730 days.
First day of non-persistence in relation to the index date.
Table 2.
Sensitivity analysis (S1): Proportion of profiles of compliant patients for three different thresholds of MPR.
Table 3.
Sensitivity analysis (S2): Proportion of profiles of persistent patients for three different definitions for the tolerable gap in medication profiles.