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Fig 1.

Testing algorithm for recent infection.

The figure shows the multi-assay algorithm that was applied for the 2012 HIV incidence estimation on confirmed HIV-positive samples from individuals 2 years and older. The algorithm used the Limiting-Antigen Avidity assay (LAg-Avidity EIA) in combination with testing for antiretroviral drugs (ARV) and HIV-1 viral load (VL copies/mL).

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Fig 1 Expand

Table 1.

Comparison of EPP/Spectrum and Thembisa: Model inputs and assumptions for adult HIV incidence estimation.

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Table 1 Expand

Fig 2.

HIV prevalence trends by age group and survey year, South Africa 2005–2012.

HIV prevalence among youth aged 15–24 years and adults aged 25–49 years estimated in the years 2005, 2008 and 2012. Source: Human Science Research Council Surveys [3].

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Fig 2 Expand

Table 2.

Comparison of South African national HIV incidence estimates, 2005–2012.

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Table 2 Expand

Fig 3.

HIV incidence by age group and estimation method, South Africa 2012.

2012 HIV incidence rates (males and females combined) for the age groups 15–49 years, 15–24 years and 25–49 years provided by the four different estimation methods (LAg-Avidity/ARV/VL, Synthetic cohort, EPP/Spectrum, Thembisa). The error bars show the 95% uncertainty interval.

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Fig 3 Expand

Table 3.

Assay- based HIV incidence and FRR by testing component, South Africa 2012.

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Table 3 Expand