Fig 1.
Footnote: LTFU—Lost to follow-up. * two of these 3 deaths occurred on the day of delivery. $ missed subsequent visit but remained in follow up. # numbers shown at post-partum include 8 and 9 women in IPTp-SP and ISTp-AL groups respectively who were not seen at delivery but who remained in follow-up.
Table 1.
Baseline characteristics of the study participants.
Fig 2.
Non-inferiority plots for primary outcomes and mean birth weight.
The figures show two-sided 90%, 95% and 99% confidence intervals (largest to smallest vertical bars, respectively), equivalent to one-sided 95%, 97.5% and 99.5% confidence intervals. The dashed blue vertical line indicates the non-inferiority margin. ATP, according to protocol population (adjusted for site); adjusted, ATP population adjusted for site, gravidity, age group, gestational age, ITN use and socio-economic status; ITT, intention to treat, (adjusted for site). Numbers included in the analyses and numeric values of the estimates are provided in the supplement (S4 Table).
Table 2.
Risk of low birth weight and anemia by intervention group.
Fig 3.
Distribution of birth weight (A) and hemoglobin concentration (B) at fourth ANC visit by intervention group.
Birth weight distributions were estimated using data from 2183 women in the IPTp-SP group and from 2208 women in the ISTp-AL group. Hemoglobin distributions utilise data from 1534 women in the IPTp-SP group and from 1600 women in the ISTp-AL group.
Table 3.
Prevalence of placental malaria by study group.
Table 4.
Adverse birth outcomes and deaths.