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Fig 1.

Exonic regions coverage.

Percentage of exonic regions covered at a read depth ≥ 5, an alignment score ≥ 10, a basecall quality ≥ 10 from WGS subsets of the original full set with different average X-fold coverage values.

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Fig 1 Expand

Table 1.

Concordance of genotypes represented in VCF and gVCF files with those detected by the MI RISK Plus kit.

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Table 2.

Genotyping of GWAS catalog sites using the VCF and gVCF file formats and the number of homozygous reference sites and no-calls based on WGS data.

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Table 3.

Genotyping of known SNPs from dbSNP 141 using the VCF and gVCF file formats and the number of homozygous reference sites and no-calls based on WGS data.

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Table 4.

Genotyping of known SNPs from ClinVar using the VCF and gVCF file formats and the number of homozygous reference sites and no-calls based on WGS data.

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Table 5.

Comparison of the content and size of different standard file formats for the storage of genomic data.

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Table 6.

Compatibility of the eVCF file format with different variation analysis suites.

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Table 7.

Comparison of the number of dbSNP, ClinVar and GWAScat sites represented using VCF, gVCF and eVCF files.

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