Fig 1.
(a) A sample breast cancer treatment plan, (b) diagnosed with RP at 3 months after RT, (c) diagnosed with RP image fused with the original isodose curves.
Abbreviation: RP: radiation pneumonitis; RT: radiotherapy.
Table 1.
Characteristics of patients.
Table 2.
Candidate predictive factors initially.
Table 3.
Predictive factors correlation ranked by LASSO.
Table 4.
Multivariate logistic regression coefficients and odds ratios for the NTCP model.
Fig 2.
The receiver operating characteristic curves (ROC) of the five normal tissue complication probability models for symptomatic radiation pneumonitis in breast cancer patients treated with hybrid IMRT.
Five factors: IV20, energy, age, body mass index (BMI) and T stage.
Table 5.
System performance evaluation.
Fig 3.
The univariate logistic normal tissue complication probability models with (a) IV20 and (b) AIV20 for symptomatic radiation pneumonitis in breast cancer patients treated with hybrid IMRT.
Abbreviation: IV20: ipsilateral lung volume received >20Gy (%); AIV20: absolute ipsilateral lung volume received >20Gy (cc); IMRT: intensity modulated radiotherapy.