Table 1.
Experimental Design—Vaccinationa.
Table 2.
Experimental Procedures and Schedule.
Fig 1.
Ig anti-PA ELISA values (μg/mL).
(A) generated from vaccinated wild type and (B) mutant rPA (geometric mean with error bars representing the 95% confidence interval).
Table 3.
Study Summary of Fate and Immune Status Relevant to B. anthracis Challenge on Day 70.
Table 4.
p Values Associated with Comparison of Ig anti-PA Values between Vaccine Groups as Analyzed by Repeated Measures ANOVA.
Fig 2.
rPA antibody-specific Toxin Neutralization Assay (TNA) and ED50 values (μg/mL).
(A) generated from vaccinated wild type and (B) mutant rPA (geometric mean with error bars representing the 95% confidence interval).
Table 5.
p Values Associated with Comparison of ED50 Values between Vaccine Groups as Analyzed by Repeated Measures ANOVA
Fig 3.
Kaplan-Meier Survival Curve of vaccinated, unvaccinated control, and sham vaccinated control rabbits.
Table 6.
Summary of Recovery of B. anthracis from Select Tissues of Inhalational Spore Challenged New Zealand White Rabbits.
Fig 4.
Recovery of B. anthracis from Select Tissues of vaccinated, unvaccinated control, and sham vaccinated control rabbits.
Table 7.
Incidence of Pulmonary Microscopic Findings in the Lungs of B. anthracis Spore Exposed Rabbits by Group (values represent the number of animals within a study group that possessed the finding).