Fig 1.
Daily Telemetry Blood Pressure Measurements by Group.
Mean and standard deviations for systolic (top) and pulse (bottom) blood pressure via implanted telemetry devices for mice as a function of the number of days they were continuously infused with ‘AngII’ (red) or saline (‘Control’; blue). The filled circles represent data recorded during the light cycle; empty circles report data from the dark cycle.
Table 1.
Descriptive Statistics for Telemetry Blood Pressure Measurements over Time.
Fig 2.
Circadian Changes in Blood Pressure Measurements by Group.
Mean and standard deviations of individual subject differences in systolic (top) and pulse (bottom) blood pressure between the dark and light circadian cycles via implanted telemetry devices for mice as a function of the number of days they were continuously infused with ‘AngII’ (red) or saline (‘Control’; blue).
Fig 3.
Comparison of Conscious and Anesthetized Blood Pressures.
Left Panels- Scatterplot comparison of systolic (top) and pulse (bottom) arterial pressure measurements via implanted telemetry under conscious (blue) and anesthetized (red) conditions. Horizontal bars represent the measurement mean. Right panels- Scatterplot of the differences between conscious and anesthetized measurements on a subject-by-subject basis. Circles denote subjects infused with AngII while ‘x’s denote controls. Horizontal bars represent the measurement mean.
Fig 4.
Comparison of Simultaneous Measurements of Implanted Telemetry and Non-Invasive Tail-cuff.
Bland-Altman plot comparing telemetry and tail-cuff measurements of systolic (top) and pulse (bottom) blood pressures. Circles denote subjects infused with AngII while ‘x’s denote controls. Overlaid numbers represent the measurement bias (adjacent to the dotted lines) and 95% limits of agreement (adjacent to solid lines). The mean coefficient of variation (CoV) is also reported.
Fig 5.
Comparison of Individual Pulse Pressure Measurements under Anesthesia to Conscious Group Average.
Bland-Altman plot comparing individual telemetry assessments of pulse pressure under anesthesia and the corresponding group averaged conscious pulse pressure for the same day. Circles denote subjects infused with AngII while ‘x’s denote controls. Overlaid numbers represent the measurement bias (adjacent to the dotted lines) and 95% limits of agreement (adjacent to solid lines). The mean coefficient of variation (CoV) is also reported.
Fig 6.
Error Analysis of Pulse Pressure Estimation for Distensibility Calculations by Group.
Mean group errors for the calculation of aortic distensibility introduced by the group-averaged estimation of arterial pulse pressure as a function of the time (days) with continuous infusion of AngII (after removal of statistical outlier) or saline (‘Control’).