Fig 1.
Study Flow Chart with Inclusion and Exclusion Criteria.
*e.g., cancer, heart surgery, traumatic brain injury, brain tumor, multiple sclerosis, stroke (as documented by evaluating neuropsychologist). **e.g., myoclonus, dystonia, parkinsonism.
Table 1.
Patient Characteristics at Baseline Neuropsychological Evaluation.
Table 2.
Logistic regression analyses, Self-reported LD and Atypical AD (vs. Typical AD).
Table 3.
Characterization of subjects with Possible or Probable LD.
Fig 2.
Conceptual Map of Pathological Links Between Developmental Learning Disabilities and Region-Specific Neurodegeneration.
In the model shown above, atypical connectivity associated with learning disabilities, in the presence of aging and other dementia risk factors, serves as the primary impetus for metabolic failure in the related brain network, which subsequently leads to region-specific neurodegenerative pathology.