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Table 1.

Checklist for quality assessment of cohort and case-control study.

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Fig 1.

Flow diagram of included studies.

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Table 2.

The baseline characteristics of included studies.

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Fig 2.

Forest plot of association between GBCAs and the development of NSF.

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Fig 3.

Cumulative meta-analysis plot of GBCAs group vs Control group.

We added one study at a time chronologically until all studies were included.

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Fig 4.

Funnel plot for publication bias.

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Fig 5.

Sensitivity analysis plot of GBCAs group vs Control group.

To assess the influence of single study on pooled estimate, we omitted one study at a time.

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Table 3.

Quality assessment of included studies.

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Table 4.

Subgroup analyses on the incidence of NSF in various conditions.

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Fig 6.

Forest plot of association between Gadodiamide exposure and the development of NSF.

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Fig 7.

Sensitivity analysis plot of gadodiamide group vs. control group.

To assess the influence of single study on pooled estimate, we omitted one study at a time.

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Fig 7 Expand

Table 5.

Dose-response relationship between gadolinium and NSF.

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Table 5 Expand