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Fig 1.

Flowchart of study selection.

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Table 1.

Characteristics of studies associating PCT level with mortality.

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Table 2.

Characteristics of studies associating PCT non-clearance with mortality.

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Fig 2.

Deek’s funnel plot asymmetry test for publication bias

(A. For single procalcitonin concentration; B. For procalcitonin non-clearance). Potential publication bias exists (P<0.05).

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Fig 3.

Forest plot of procalcitonin concentration to predict mortality in sepsis.

The overall pooled RR was 2.60 (95% CI, 2.05–3.30).

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Fig 4.

Summary receiver operating characteristic graph of the included studies

(A. For single procalcitonin concentration; B. For procalcitonin non-clearance).

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Table 3.

Subgroup analysis.

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Table 3 Expand

Fig 5.

Forest plot of procalcitonin non-clearance to predict mortality in sepsis.

The overall pooled RR was 3.05 (95% CI, 2.35–3.95).

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