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Fig 1.

Frequency distribution curve for nine agronomic traits including 1000 grain weight in 207 Indian wheat genotypes used in association mapping study.

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Table 1.

Descriptive statistics for 1000 grain weight and other agronomic traits.

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Table 1 Expand

Fig 2.

Representative gel picture of PCR amplification of promoter region of TaGW2-6A gene in 15 Indian wheat genotypes.

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Table 2.

Summary of four SNPs (identified by sequence alignment) with their position, variation, frequency and count.

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Table 2 Expand

Table 3.

Summary of marker-trait association using single SNP for 1000 grain weight.

Significantly associated SNP is marked with *.

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Table 3 Expand

Table 4.

Marker-trait association of SNP-494 with 1000 grain weight and other eight agronomic traits.

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Table 4 Expand

Fig 3.

Five haplotypes with single nucleotide polymorphisms (SNPs) in the promoter regions of TaGW2-6A.

Frequency of each haplotype is given in parentheses. SNPs are highlighted with yellow (G allele) and red (A allele) colours. CGCG motif is shown in a box. Significant difference of mean TGW (g) is represented by bars. Haplotypes covered by a single bar represent no significant difference for TGW and vice-versa.

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Table 5.

Analysis of variance for TGW using five different haplotypes.

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Table 5 Expand

Fig 4.

Bar diagrams showing (A) relative expression level of TaGW2-6A in immature seeds at 15dpf.

Actin gene was used as the endogenous control and variety HI 1500 used as reference; (B) TGW of varieties having SNP-494_A on the left panel and those with SNP-494_G in the right panel.

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Fig 5.

Plot showing significant regression of (A) TaGW2-6A expression level and thousand grain weight (TGW) in genotypes with two different alleles (A and G) of SNP-494 identified in promoter region, and (B) TGW with relative expression level in same genotypes.

* and ** indicate significance at 0.05 and 0.01 levels, respectively.

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Fig 6.

Validation of CAPS in genotypes with causal SNP_G and SNP_A on 2% agarose gel.

G and A represent undigested PCR products of genotypes with SNP_G and SNP_A; G1–G4 and A1–A4 are genotypes with SNP_G and SNP_A after digestion with FauI, M = marker.

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Fig 7.

A hypothetical pathway of CGCG mediated regulation of TaGW2-6A.

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