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Table 1.

Summary of available literature on gastrointestinal pH measurement with freely moving devices in healthy volunteers and / or inflammatory bowel diseases.

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Table 2.

Demographics of included subjects (healthy volunteers).

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Table 2 Expand

Fig 1.

Flowchart.

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Table 3.

Study schedule, activities are marked with an X (T0 is 8 a.m.).

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Fig 2.

Mean (gastrointestinal residence and transit times determined with the IntelliCap system.

Data are presented mean and standard deviation of 13 evaluable subjects (for CTT and WGTT n = 9).

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Fig 3.

Example of pH-profile of the first 10 hours after intake of the IntelliCap capsule (subject 14).

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Fig 4.

Summary of pH in the stomach, small intestine and colon as measured with the IntelliCap system.

Data are presented as mean and standard deviation of 15 evaluable subjects.

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Fig 5.

Colon arrival time based on pH (-) corresponds with release of 13C (♦) (subject 14).

See also Fig 4 for the first 10 hours.

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Fig 6.

Difference (delta T) between lag-time (based on isotope signal) and CAT (based on pH) for each subject (n = 12).

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