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Fig 1.

Morphologic and Phylogenetic analysis of different-colored mutants of Cymbidium sinense 'Dharma.'

(A) The UPGMA cluster of ten leaf-color mutants of Cymbidium sinense 'Dharma' based on AFLP markers; (B) Morphologic characteristics of six leaf-color mutants of Cymbidium sinense 'Dharma' studied in this work.

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Fig 2.

The variations in the contents of photosynthetic pigments between the wild type and leaf-color mutants.

(A) Chlorophyll content in wild-type and color-mutant leaves of Cymbidium sinense 'Dharma'(mg g-1 FW); (B) The relative contents of chlorophyll synthesis precursors PBG, Proto IX, Mg-Proto, and Pchlide, and chlorophyll degradation metabolite Pheide a (Take each intermediate product content in the wild type as 100%, comparing it with its mutant correspondent). Values are means ±standard deviation (n > 10). Mean-Whitney U-test significant at *P<0.05 between the mutants and the wild type control.

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Fig 3.

The size distribution of assembled isotigs.

The x-axis represents the sequence length in base pairs. The y-axis represents the isotigs number.

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Table 1.

Summary of sequencing and de novo assembling of the transcriptome in Cymbidium sinense 'Dharma'.

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Table 2.

Summary of the blast hits against the known protein database.

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Fig 4.

Characteristics of homology search of the isotigs.

(A) Similarity distribution of the best Blast hits in Nr database; (B) Similarity distribution of the best Blast hits in Uniprot database; (C) Similarity distribution of the best Blast hits in Swissport database.

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Fig 5.

GO classification of unigenes of assembled isotigs.

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Fig 6.

KOG function classification of assembled isotigs.

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Table 3.

Functional categories of assembled isotigs in KEGG pathways.

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Fig 7.

Assembled isotigs involved in the chlorophyll biosynthesis pathway pathway of Cymbidium sinense 'Dharma'.

Abbreviation: HEMC, hydroxymethylbilane synthase; HEMD, uroporphyrinogen-III synthase; HEME, uroporphyrinogen decarboxylase; CHLH, magnesium chelatase; CHLD, magnesium chelatase subunit ChlD; CHLI, magnesium chelatase subunit ChlI; CHLM, magnesium-protoporphyrin O-methyltransferase; PORA, protochlorophyllide oxidoreductase A; CHLG, Chlorophyll synthase; CAO, chlorophyllide a oxygenase.

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Table 4.

Putative key enzyme-encoding genes in chlorophyll metabolism pathway.

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Fig 8.

Assembled isotigs involved in the chlorophyll degradation pathway pathway of Cymbidium sinense 'Dharma'.

Abbreviation: NOL, chlorophyll b reductase; CLH, chlorophyllase; PAO, pheophorbide a oxygenase, RCCR, red Chl catabolite reductase.

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Fig 9.

Northern blotting analysis of the expression of identified genes in different tissues of Cymbidium sinense 'Dharma'.

Each lane contained 15 g total RNA isolated from roots, pseudobulbs and six-month old leaves, rRNA served as a loading control (bottom of the panel).

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Fig 10.

Gene expression analysis.

The qRT-PCR analysis of the expressions of two enzyme-encoding genes in chl degradation pathway (A) and five key enzyme-encoding genes in chl biosynthesis pathway (B). The y-axis indicates fold change in expression among the samples. The Lg(Relative Quantitation) of the genes in the wild-type leaves was calibrated as zero. RNA was extracted from six-month-old normal growth leaves. ACT gene served as the internal control. Error bars indicate the standard deviation of the mean (SD) (n = 3). Three biological replicates were analyzed, with similar results.

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