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Table 1.

Details about sequence-derived features.

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Fig 1.

The flowchart of GA-based ensemble method.

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Table 2.

The average AUC scores of individual feature-based models using different values for λ, evaluated on IMMA2 by 20 independent runs of the 10-CV.

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Table 3.

The average performances of different individual feature-based models, evaluated on IMMA2 by 20 independent runs of the 10-CV.

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Table 4.

The absolute values of correlation coefficients of AUC scores yielded by individual feature-based models

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Table 5.

The average performances of models merging different feature vectors, evaluated by 20 independent runs of the 10-CV.

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Table 6.

The average performances of GA-based ensemble method on benchmark datasets, evaluated by 20 runs of 10-CV.

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Table 7.

The frequencies of features in the optimal feature subsets.

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Table 8.

The average performances of different models evaluated by 20 independent runs of 10-CV.

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Table 9.

The statistics of improvements over benchmark methods (significance level 0.05).

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