Table 1.
Angiogenesis-related protein markers analyzed in the study.
Fig 1.
Brain MRIs of a term asphyxiated newborn treated with hypothermia, performed on day 9 of life.
(A) The T2-weighted imaging shows the injury within the thalami and lentiform nuclei (arrows).
Table 2.
Clinical characteristics of the asphyxiated newborns treated with hypothermia.
Fig 2.
Expression of angiogenesis-related protein markers at 24 hours of life.
Mean concentrations in each group were compared. p values were calculated to highlight significant protein expression differences between the groups (* p < 0.05). For graphical representation, ratios between group mean concentrations were calculated and log transformed to obtain fold change data for each marker. (A) Fold changes in protein expression between asphyxiated newborns treated with hypothermia and healthy newborns. (B) Fold changes in protein expression between asphyxiated newborns developing and not developing brain injury.
Fig 3.
Evolution of angiogenesis-related protein expression over time in asphyxiated newborns developing brain HI injury compared to asphyxiated newborns not developing brain HI injury.
The heat map depicts the fold changes in protein concentration between the two groups. Fold change ranges are denoted by the color coding in the legend at the right. ** p < 0.05.