Fig 1.
Accrual flowchart of the families and the individuals selected from the Database.
Table 1.
Number of cancer locations according to diagnosed mutation (% of members(*)).
Fig 2.
Cancer locations predicting the BRCA mutational risk.
(logistic regression: p-values complete the information given by each Odds-Ratio; error bars represent 95%-CI of Odds-Ratios; covariates are cancer locations and "Breast < 30" means female breast cancers occurring before 30 years…).
Table 2.
Fertility parameters depending on the presence of a BRCA mutation in the family: p-values correspond to tests performed between BRCA1+2 mutated families versus not mutated ones (NM).
Table 3.
Influence of new natality parameters on the risk for BRCA mutation when analyzed concurrently with cancer locations and age at diagnosis.
Table 4.
Fertility parameters in 1,546 BRCA-tested individuals according to their BRCA mutational status and if they belong or not to a BRCA mutated family.