Fig 1.
Procedure of CT data processing.
Fig 2.
Landmarks on the skull surfaces and suture-bone boundaries.
Note: B01 to B24 represent landmarks located at the skull (bone) surface, S01 to S32 represent landmarks located at the suture center lines, and C01 to C04 represent landmarks located at the intersections of the sutures. Landmarks on the skull surface are generally evenly distributed on the reference curves. For example, landmark No. B12 on the skull surface is midway between landmarks No. S27 and S14; and landmark No. B14 is in the middle of landmarks No. B12 and S14.
Fig 3.
Pediatric head circumference and CirOffset relative to the CDC median head circumference curve.
Fig 4.
Box plots of signed error in mm between predicted landmark coordinates and the actual landmarks collected from CT data of sampled six subjects.
Top row represents the age in month and the head circumference in cm of the subjects.
Fig 5.
Comparison between model predicted skull geometry and segmented CT geometry.
Fig 6.
Skull size/shape and suture changes by age.
Fig 7.
Head size/shape and suture variation among 1.5 YO children.
Table 1.
Results from the linear mixed regression model.
Fig 8.
Skull thickness distribution by age.
The models shown here were generated by morphing a template mesh into the model-predicted skull geometry using a Radial Basis Function. The color contours were generated based on the skull thickness values associated with each node on the morphed mesh. The quantitative skull thickness data corresponding to each landmark location can be found in Table D in the S1 Appendix.
Fig 9.
Skull thickness distribution variation among 1.5 YO children with a range of head circumference.
The models shown here were generated by morphing a template mesh into the model-predicted skull geometry using a Radial Basis Function. The color contours were generated based on the skull thickness values associated with each node on the morphed mesh. The quantitative skull thickness data corresponding to each landmark location can be found in Table D in the S1 Appendix.