Table 1.
Demographics for the biopsy groups.
Fig 1.
Inflammatory cytokines in bronchial biopsies (MCP-4, IL-5, IL-13 and TARC) in CRSwNP patients and controls, stratified by asthma severity.
Log transformed data, concentrations in pg/mL. I = Intermittent; MiP = Mild persistent; MoP = Moderate persistent; SP = Severe persistent. P-values represent comparison by Kruskal-Wallis test. In this analysis we included biopsies from controls with asthma that were not included in the inter-group analyses. This analysis indicates that bronchial inflammation increases with increasing asthma-severity.
Table 2.
Comparison of cytokines in CRSwNP with/without asthma and controls.
Fig 2.
Concentration of Th1 and Th2 cytokines in nasal polyps, ITs and bronchial biopsies in CRSwNP patients.
A: Th1 cytokines. B: Th2 cytokines. Log transformed data, concentrations in pg/mL. NP = nasal polyp, BB = bronchial biopsy, IT = inferior turbinate. P-values represent comparison by a paired Wilcoxon signed rank test. Both CRSwNP patients with and without asthma are included in this analysis. All Th2 cytokines were increased in the nasal polyps compared to the bronchii; this difference was not seen for Th1 cytokines.
Table 3.
Correlation individual cytokines in the nasal polyps and bronchial biopsies.